Plasma Cystatin C Is Superior to 24-h Creatinine Clearance and Plasma Creatinine for Estimation of Glomerular Filtration Rate 3 Months after Kidney Transplantation

Plasma cystatin C is superior to 24-h creatinine clearance and plasma creatinine for estimation of glomerular filtration rate 3 months after kidney transplantation.

To the Editor: In a recent report (1 ), we provided data on the early follow-up of renal function by plasma cystatin C in transplanted adults. Cystatin C was found to be an alternative and more sensitive marker of acute changes in glomerular filtration rate (GFR) than plasma creatinine, especially during acute rejection episodes. We present here some additional data on the same group of patient...

Estimation of glomerular filtration rate from height/plasma creatinine ratio.

Glomerular filtration rate determination by creatinine and cystatin-C in patients with acute pyelonephritis

Background: Measurement of glomerular filtration rate (GFR) and monitoring of it in any patient on nephrotoxic drugs is very important. Recently, cystatin C (cys-C) has been introduced as a better marker for determining and monitoring renal function than creatinine especially in a mild decrease of GFR. This study was done to assess the change of GFR measurement based on serum Cys-C and creatini...

serum cystatin-c is not superior to serum creatinine in predicting glomerular filtration rate in cirrhotic patients

background assessment of glomerular filtration rate (gfr) by common creatinine-based methods is potentially inaccurate in patients with cirrhosis. cirrhotic patients have several underlying conditions that contribute to falsely low serum creatinine concentrations, even in the presence of moderate to severe renal impairment. therefore creatinine-based methods usually overestimate true gfr in the...

The assessment of glomerular function: creatinine clearance or plasma creatinine?

Plasma creatinine concentration is superior to creatinine clearance for the detection of abnormal glomerular function, of changes of glomerular function in patients with chronic renal disease. Creatinine clearance should be abandoned as the routine assessment of glomerular function.